联系方式:E-mail:
lzpbd@hbu.edu.cn
二、主讲课程及研究方向
1.主讲课程:分子光谱分析
2.研究方向:分子发光与生化分析。
三、代表性论文
1.
Yongqiang Cheng, Xian Zhang, Zhengping
Li*, Xiaoxia Jiao, Yucong
Wang, Yali Zhang, Highly Sensitive Determination of microRNA Using
Target-Primed and Branched Rolling Circle Amplification, Angewandte Chemie International
Edition, 2009, 48, 3268-3272. (Highlighted Paper)
2.
Hongxia Jia, Zhengping Li*, Chenghui Liu, Yongqiang Cheng,
Ultrasensitive Detection of microRNAs with Exponentially Isothermal
Amplification, Angewandte Chemie International Edition, 2010, 49, 5498-5501.
3.
Pengbo Zhang, Jiangyan Zhang, Chengli Wang, Chenghui Liu, Hui Wang, and Zhengping Li*, Highly Sensitive and Specific Multiplexed MicroRNA
Quantification Using Size-Coded Ligation Chain Reaction, Analytical Chemistry, 2014, 86, 1076-1082.
4.
Bai Jie, Zhao Yunjie, Wang Zhibin, Liu Chenghui*, Wang Yucong, Li Zhengping*. Dual-Readout Fluorescent Assay of Protein Kinase Activity
by Using TiO2-Coated Magnetic
Microspheres. Analytical Chemistry, 2013, 85, 4813-4821.
5.
Yongqiang Cheng,* Qing Du, Liyong Wang, Hailian Jia, and Zhengping Li*,Fluorescently
Cationic Conjugated Polymer as an Indicator of Ligase Chain Reaction for
Sensitive and Homogeneous Detection of Single Nucleotide Polymorphism. Analytical
Chemistry, 2012, 84, 3739−3744.
6.
Chenghui Liu*, Zhe Wang, Hongxia Jia, Zhengping
Li*, Efficient
fluorescence resonance energy transfer
between upconversion nanophosphors
and graphene oxide: a highly sensitive biosensing
platform, Chemical Communications, 2011, 47, 4661–4663.
7.
Cuiping Li, Zhengping Li*, Hongxia Jia and Jingli Yan,
One-step ultrasensitive detection of microRNAs with loop-mediated isothermal
amplification (LAMP), Chemical Communications, 2011, 47,
2595–2597.
8.
Jingli Yan, Zhengping Li*, Chenghui Liu, Yongqiang Cheng, Simple and
sensitive detection of microRNAs with ligase chain reaction, Chemical
Communications, 2010, 46, 2432-2434.
9.
Jinzhao Song, Zhengping Li*, Yongqiang Cheng, Chenghui Liu,
Self-aggregation of oligonucleotide-functionalized gold nanoparticles and its
applications for highly sensitive detection of DNA, Chemical Communications, 2010, 46, 5548-5550.
10.
Yali Zhang, Zhengping Li*, Yongqiang Cheng, Xuechong Lv,
Colorimetric detection of microRNA and RNase H activity in homogeneous solution
with cationic polythiophene derivative, Chemical Communications, 2009, 45,
3172-3174.
四、科研项目
1. 高灵敏度分子诊断分析研究(项目批准号:20925519),国家杰出青年基金(200万元,2009年-2013年,主持人:李正平)
2.
基于核酸探针可控自组装的小RNA活体细胞成像分析(项目批准号:91127035),国家自然科学基金重大研究计划(70万元,2012年-2014年,主持人:李正平)
3.
基因单核苷酸多态性的均相高灵敏度光散射分析(项目批准号:20875021),国家自然科学基金(36万,2009年-2011年,主持人:李正平)
4.
MicroRNA的高灵敏度检测及其生物功能研究(项目批准号:2009001525),河北省杰出青年基金(30 万,2009年-2011年,主持人:李正平)
五:获奖情况
1、利用分子发光技术研究高灵敏度分子诊断分析,2010年度河北省自然科学奖一等奖(2010ZR1002-1),李正平、杜保安、成永强、王愈聪、刘成辉
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